Alanine Aminotransferase and Aspertate Aminotransaminase Activities in Wistar Rats Fed with Musa paradisiaca (Plantain) Stem Pulp in Aluminium Chloride Induced Hepatic Oxidative Stress

In this study, the effect of Musa paradisiaca (plantain) stem pulp on aluminium chloride (AlCl3) induced hepatotoxicity was studied. Fifteen (15) healthy female wistar rats after acclimatization for two weeks were randomly distributed to three (3) groups, with five (5) in each group. Group 1 served as control and received pelletized growers feed distilled water throughout experiment (14 days). 2 100mg/kg/body weight (b.w.) fed 14 days group 3 100mg/kgb.w 2mL/kg juice gotten from M. also allowed free access ad libitum days. Blood samples collected via cardiac puncture analyzed AST, ALT, MDA SOD. Results revealed that there a significant increase AST ALT levels respectively 67.83±1.39 173.40±0.81 43.73±1.00 128.24±0.68 treatment AlCl3 compared while administration extract ameliorated adverse effects when treated groups 72.40±1.71 45.83±1.22 respectively. There decrease (P<0.05) SOD level 6.04± 0.49 2.56±0.86 6.00±1. 56 observed It 401.09±0.10 1207.98±1.39 388.83±31.15 groups. showed mitigating chloride-induced thus justifying hepatoprotective property paradisiaca.